botox® is used extensively as a medicine due to its ability to reduce muscle contractions. botox® is a derivative of botulinum toxin; there are seven different types of botulinum toxin (A, B, C1, D, E, F, and G). The Medicine botox® is derived from botulinum toxin type A and has been tested by many physicians and has subsequently become a relatively common drug to treat many different types of medical conditions. Many common medicines, such as penicillin and other antibiotics are in fact derived from botulinum toxin type A. botox® has been around as a medicine for decades. botox® is produced by Allergan Inc; botox® Cosmetic is a purified protein produced by the Clostridium botulinum bacterium. As a cosmetic treatment botox® treats wrinkles that are caused by muscle contraction. Wrinkles such as frown lines, crow's feet, forehead creases are treated with botox®.
Botulinum toxin type A is purified into a protein that blocks the release of acetylcholine. The effects of botox® are 100% reversible but botox® typically lasts for a few months. botox® is usually injected into treated areas. The effect of botox® is to temporarily weaken overactive muscles. Because of this effect botox® has become very popular to treat a variety of muscular and neurological disorders.
History of botox®
The first use of botox® in the medical field occurred in the 1960s to treat neurological disorders. In 1989 botox® was approved by the FDA to treat certain eye muscle disorders such as uncontrollable blinking and crossed eyes. In 2000, botox® was approved to treat a condition that causes acute neck and shoulder contractions. botox® was first considered as a cosmetic treatment when physicians noticed that in cases where it was used to treat facial muscles frown lines between the eyebrows were reduced as a side effect.
In 2001 Health Canada approved botox® for the treatment
of frown lines. (botox® has been approved in Canada since
1990 to treat disorders caused by overactive muscles).
In 2002, the FDA approved botox® and it was indicated
for reduction of the frown lines for up to four months
after its administration. botox® is currently under review
for indication to treat migraine headache, tension headache,
and cerebral palsy. botox® is the most popular non-surgical
cosmetic procedure performed. In the year 2003 there
were over 2 Million botox® injections performed.